creutzfeldt-jacob disease: a case report.
نویسندگان
چکیده
creutzfeldt-jacob disease is a prion disease which has a wide range of clinical presentations. its diagnosis is not simple and clinical manifestation along with eeg, mr imaging findings and cerebrospinal fluid (csf) analysis should be considered for a definite diagnosis. a-50-year-old woman referred with cognitive impairment, myoclonic jerks, mutism and difficulty in swallowing to our clinic. eeg (electroencephalography) results showed bilaterally periodic sharp and slow-wave discharges. protein 14-3-3 in csf was detected. magnetic resonance imaging (mri) findings revealed hyperintensity of the caudate and putamen in diffusion-weighted imaging (dwi), t2 weighted (t2w) sequences and fluid-attenuated inversion-recovery (flair) images. patients who have progressive dementia should be evaluated by means of mr imaging and csf analysis for cjd specific proteins should be considered.
منابع مشابه
Creutzfeldt-Jacob Disease: a case report
Creutzfeldt-Jacob disease is a rare, neurodegenerative disease caused by a prion protein. The patients are usually between 40 and 60 years old. Most of the patients die within one year after onset of the disease. A typical case is reported. It is pointed out that such a dramatic development can cause anxiety and a feeling of inadequacy for close relatives. To avoid adverse consequences, it is i...
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عنوان ژورنال:
acta medica iranicaجلد ۵۲، شماره ۶، صفحات ۴۸۸-۴۸۹
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